Top stories in hematology/oncology: FDA approves ibrutinib in 'practice-changing breakthrough …

Among the top stories in hematology/oncology is a possible practice-changing breakthrough with the FDA approval of ibrutinib for adults with chronic graft-versus-host disease. Women with breast cancer and a high BMI experienced improved aromatase inhibitor-associated arthralgia symptoms after treatment with omega-3 fatty acids. Other top stories include an editorial examining the concept of genome-driven oncology, a phase 2 trial showed that intralesional agent SD-101 plus pembrolizumab induced a high response rate with a tolerable safety profile, and 70 NCI-designated cancer centers in the U.S. issued a joint statement calling for increased gender-neutral HPV vaccination and evidence-based screening.

GVHD management improves, but questions remain about risk stratification, prophylaxis

The FDA approval of ibrutinib for adults with chronic graft-versus-host disease may herald a practice-changing breakthrough in the management of this posttransplant complication. Read More.

Omega-3 fatty acid use improves symptoms among obese patients with breast cancer

Aromatase inhibitor-associated arthralgia symptoms improved among women with breast cancer and a high BMI after treatment with omega-3 fatty acids, according to findings presented at ASCO Annual Meeting. Read More.

Delivering on the promise of precision oncology

The concept of genome-driven oncology became a reality almost 20 years ago with the introduction of imatinib, targeted to the ABL kinase. Read More.

Combination therapy with SD-101, pembrolizumab shows promise for metastatic melanoma

Intralesional agent SD-101 plus pembrolizumab induced a high response rate with a tolerable safety profile among a small cohort of patients with metastatic melanoma, according to results of a phase 1b/phase 2 trial presented at ASCO Annual Meeting. Read More.

Cancer centers join forces to eliminate HPV-related cancers

The nation’s 70 NCI-designated cancer centers issued a joint statement today calling for increased gender-neutral HPV vaccination and evidence-based screening in hopes of eliminating cancers caused by the virus. Read More.

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